Evaluation of tryptophan role on some biochemical and histological alterations in irradiated rats
نویسندگان
چکیده
The effect of tryptophan daily oral dose (81.7 mg/kg wt) for 21 days on some biochemical and histological parameters in female albino rats exposed to gamma irradiation at dose 7 Gray (Gy) was investigated. The hematological studies revealed that there were significant reduction in red blood cell count, hemoglobin, hematocrit, platelets and leucocytes values in irradiated rats and elevation of thiobarbituric acid reactive substances level. Catalase activity decreased significantly after irradiation. Some histological changes were noticed in both lymph nodes and spleen of irradiated rats. Tryptophan administration dose (81.7 mg/kg wt) revealed ameliorative effects in mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration and some biochemical and histological changes occurred due to gamma irradiation.
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